How chandelier cells light up the brain

(Cold Spring Harbor Laboratory) Chandelier cells stand out among brain cells for their elaborate, branching structure. A single chandelier cell reaches out to connect and communicate with more than 100 other neurons. Abnormalities in chandelier cells have been linked to epilepsy, autism, and schizophrenia. However, these cells have been notoriously difficult to study as their numbers are few, so until recently, chandelier cells remained largely enigmatic.